Directions from George Best Belfast City Airport
Head South on Airport Road.  At the roundabout, take the 1st exit and stay on Airport Road.  At the roundabout take the 2nd exit.  Continue straight onto Sydenham Bypass.  Continue to follow Sydenham Bypass.  Continue onto MS Cross Harbout.  At junction 1a, exit toward A12/M1/Docks.  Turn left at A2/Nelson St.  Turn right at A2/Great Patrick Street.  Slight left at A2.  Turn left at Donegall Street.  Turn left at Talbot Street and the Midtown Center is just over half way down the street on the right hand side.

Directions from M1
Head Northeast on M1.  Continue onto A12/Westlink.  Take the exit toward A6/Clifton Street.  Turn right at A6/Clifton Street.  Continue onto Donegall Street.  Turn left at Talbot Street and the Midtown Center is just over half way down the street on the right hand side.

Directions from Belfast International Airport
Head West on A57.  At the roundabout take the 2nd exit onto A57/Airport Road.  Continue to follow A57.  At Killead roundabout take the 3rd exit onto A26/Tully Road.  At Nutts Corner roundabout take the 2nd exit onto A52/Belfast Road.  Continue to follow A52.  At Carlisle Circus take the 2nd exit.  Continue onto Donegall Street.  Turn left at Talbot Street and the Midtown Center is just over half way down the street on the right hand side.